Rituximab Maintenance for Follicular lymphoma

 


Low tumor burden :
RESORT
R x 4-> R at relapse vs R maint
No dif in TTF


High tumor burden:
PRIMA = R+CHOP/CVP/FCM ->R or no R ⬆️PFS, no dif OS
Long term f/u still no dif OS
BR = Retrospective suggests ⬆️PFS if in PR vs no R

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