REASONS FOR MUCORMYCOSIS IN COVID-19
Key Take Home Messages: § Mucormycosis is an opportunistic devastating fungal rhino-cerebro-orbital infection which is primarily a disease of sinuses and secondary to orbit. § Mucormycosis are not black fungi. It is not contagious & not spread by oxygenation, humidifier and water. § Reasons for mucormycosis in Covid-19: v affection of innate immunity v oxidative stress v iron overload v affection of adaptive immunity § Risk factors for mucormycosis in Covid-19: v uncontrolled DM v high dose and early treatment with steroids/immune-modulators/mechanical ventilation v long standing oxygen therapy v tocilizumab use v prolonged use of broad spectrum antibiotics v high levels of HbA1c, IL-6 and serum ferritin. § Prevention: v Good and proper hygiene of face and oral/buccal cavity v No role of dehumidifier bottle fluid in this scenario, so no role of methylene blue in these b...