Dr Rajesh bollam DM medical oncology and hematology ( Cancer specialist Hyderabad )

Blood Cancer – Types and Treatment Blood accounts for about 8% of our total body weight and plays a vital role in bodily functions; circulating throughout body supplying nutrients, oxygen, antibodies to each and every cell.  Blood cancer occurs due to abnormal multiplying of leukocytes (WBCs). Cancer causes an imbalance in the body due to increase in cell division, leading to excessive production of WBCs. There are three main types of blood cancers: 1. Leukemia: Cancer affecting WBCs or precursor of white blood      cells, increasing their production that can’t fight infections. This      cancer generally originates in the bone marrow rendering its      ability of red blood cells and platelets production. It is further      categorized in four types: • Acute Lymphocytic Leukemia (ALL): As the name suggests, it     affects lymphocytes in the bone marrow. Production of too many     lymphocytes r...

  Key Take Home Messages: §  Mucormycosis is an opportunistic devastating fungal rhino-cerebro-orbital infection which is primarily a disease of sinuses and secondary to orbit. §  Mucormycosis are not black fungi. It is not contagious & not spread by oxygenation, humidifier and water. §  Reasons for mucormycosis in Covid-19: v  affection of innate immunity v  oxidative stress v  iron overload v  affection of adaptive immunity §  Risk factors for mucormycosis in Covid-19: v  uncontrolled DM v  high dose and early treatment with steroids/immune-modulators/mechanical ventilation v  long standing oxygen therapy v  tocilizumab use v  prolonged use of broad spectrum antibiotics v  high levels of HbA1c, IL-6 and serum ferritin. §  Prevention: v  Good and proper hygiene of face and oral/buccal cavity v  No role of dehumidifier bottle fluid in this scenario, so no role of  methylene blue in these b...

  Clinical Pearls  #DrRajeshBollam  #Hematologist  Microcytic and Hypochromic anemia is one of the common scenario we encounter in Clinics  When we order iron studies  The following are possibilities and Probable diagnosis  *microcytic anaemia with low s.ferritin& high TIBC=iron defeciency anaemia *microcytic anaemia with high s.ferritin&low TIBC=anaemia of chronic diseases *microcytic anaemia with high s.iron= sidroblastic anaemia *microcytic anaemia with NORMAL iron studies=thalassemia  #Hematologist #Hyderabad #Telangana #DrRajeshBollam #anemia BOOK APPOINTMENT

  Updated Recommendations for Breast Cancer Surveillance in Young Female Cancer Survivors William J. Gradishar, MD reviewing Mulder RL et al. J Clin Oncol 2020 Dec 10 Surveillance is now strongly recommended for survivors treated with ≥10 Gy chest radiation — a change from ≥20 Gy. In 2013 the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) published evidence-based recommendations for surveillance of female survivors of childhood, adolescent, and young adult (CAYA) cancer who were treated with radiation to fields that potentially involved breast tissue on the chest wall. Based on new evidence, IGHG has updated its breast cancer surveillance recommendations. BOOK APPOINTMENT Modified recommendations include the following: Mammography and breast MRI should be performed at least annually up to age 60 for survivors treated with ≥10 Gy chest radiation (strong recommendation) and for those treated with upper abdominal radiation that exposed breast tiss...