AMYLOIDOSIS MONTH
5 Best Papers Tips, Tricks & Thread Diagnostic delays 3 years from symptom onset may be evaluated > 5 specialists prior to receiving the correct diagnosis vast majority of cardiac amyloidosis transthyretin amyloidosis or light chain amyloidosis “red flag” suspicion for this diagnosis ECG voltage QRS amplitude limb leads (≤0.5 mV), pseudo-infarct pattern & relative voltage QRS (S wave in V1 + Rwave in V5 or V6 ≤15 mm) in the setting of LVH on #EchoFirst AV block Echo concentric LVH, biatrial & small pericardial , apical sparing of LV strain #whyCMR Diffuse, subendocardial LGE. T1 mapping techniques & measurement of extracellular volumes #CVnuc TTR-CA 91% sens & nearly 100% spec in the absence monoclonal gammopathy Majority of false tests LC cardiac amyloidosis, exclusion LC amyloidosis is critical Several types of amyloidosis have been described based on the specific protein comprising the deposited fibrils Uncommon for secondary (AA) amyloidosis to aff...